Varicella zoster virus meningitis complicating sodium stibogluconate treatment for cutaneous leishmaniasis.
نویسندگان
چکیده
Sodium stibogluconate (Pentostam(R); GlaxoSmithKline) is a pentavalent antimonial compound used in the treatment of leishmaniasis, which has an association with reactivation of varicella zoster virus (VZV). We report the first known case of an immunocompetent adult who developed VZV aseptic meningitis and dermatomal herpes zoster during treatment with sodium stibogluconate.
منابع مشابه
Nonresponsiveness to standard treatment in cutaneous leishmaniasis: A case series from Sri Lanka
Leishmaniasis is caused by parasitic protozoa of the genus Leishmania. Cutaneous leishmaniasis (CL) is endemic in Sri Lanka with over 3000 cases during the last decade and numbers are increasing. Treatment options available in Sri Lanka for CL include intralesional/intramuscular sodium stibogluconate and cryotherapy. Eight cases of treatment failure with standard therapy are reported from the D...
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We report an imported case of cutaneous leishmaniasis in a 37-year-old man from Saudi Arabia caused by Leishmania major. He presented with non-healing nodulo-ulcerative lesions with a "volcanic crater" on the lower limbs. It was clearly cutaneous leishmaniasis - a rare disease in China - as reflected by the patient's clinical history, the lesions' morphology, histopathological examination, cult...
متن کاملHIV-1 replication is stimulated by sodium stibogluconate, the therapeutic mainstay in the treatment of leishmaniasis.
Leishmaniasis is an important opportunistic disease among patients infected with human immunodeficiency virus (HIV)-1. The pentavalent antimony compound sodium stibogluconate is a drug of choice for the treatment of leishmaniasis. Because sodium stibogluconate acts as an inhibitor of phosphotyrosyl phosphatases and such inhibitors can promote HIV-1 replication, we tested the effect of this comp...
متن کاملTransactions of the Royal Society of Tropical Medicine and Hygiene
Introduction Visceral and cutaneous leishmaniasis are endemic in the Maltese islands. Leishmania infantum has been cultured from humans, dogs and the sandfly PhZebotomus perniciosus (GRADONI et al., 1991). Since 1955 the incidence of leishmaniasis has been about 10 local new cases per year compared with about 150 cases per year in the immediate post-war period (CACHIA & FENECH, 1964; Ministry o...
متن کامل[Successful treatment of cutaneous leishmaniasis with amphotericin B; a case of unresponsive to pentavalent antimony therapy].
Cutaneous Leishmaniasis (CL) is a skin infection caused by various species of Leishmania parasites, which is transmitted by infected Phlebotomus sandfly bites. Pentavalent antimonials (meglumine antimoniate and sodium stibogluconate) are used for the treatment of adult CL patients as an effective and safe method. Liposomal amphotericin B is an alternative for the treatment of choice in cutaneou...
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ورودعنوان ژورنال:
- The American journal of tropical medicine and hygiene
دوره 74 4 شماره
صفحات -
تاریخ انتشار 2006